Hypnosis: An Altered State Of Consciousness
By Mayo Clinic staff
Have you ever been totally absorbed while reading a book or cooking or watching a movie? Did you zone out to the point where you didn’t notice what else was going on around you? If so, you have experienced a type of trancelike state or focused attention that’s similar to what happens to you during hypnosis.
Although its medical uses aren’t entirely understood, hypnosis, when provided by a certified hypnotherapist or other qualified clinician, appears to help with a variety of health conditions. These range from helping to control pain to easing the symptoms of asthma. Before considering hypnosis, learn more about how it works, what conditions it may be helpful for and what to look for in a hypnotherapist.
What is hypnosis?
Hypnosis, which is sometimes referred to as hypnotherapy or hypnotic suggestion, is an altered state of consciousness. This state of consciousness is generally artificially induced and is different from your everyday awareness. When you’re under hypnosis:
Your attention is more focused.
You’re more responsive to suggestions.
You’re more open and less critical or disbelieving.
The purpose of hypnosis as a therapeutic technique is to help you understand and gain more control over your behavior, emotions or physical well-being.
Who is Hypnosis for?
It’s not clear how hypnosis works. However, it appears to affect how your brain communicates with your body through nerve impulses, hormones and body chemicals such as neuropeptides. Hypnotherapists say that hypnosis creates a state of deep relaxation and quiets the mind. When you’re hypnotized, you can concentrate intensely on a specific thought, memory, feeling or sensation while blocking out distractions. You’re more open than usual to suggestions, and this can be used to improve your health and well-being.
Hypnotherapy has the potential to help relieve the symptoms of a wide variety of illnesses and conditions. It can be used independently or along with other treatments. For example, it’s one of several relaxation methods for treating chronic pain that has been approved by an independent panel convened by the National Institutes of Health.
According to preliminary studies, hypnotherapy can be used to:
- Treat pain during childbirth and reduce labor time
- Control bleeding and pain during dental and surgical procedures
- Relieve cramping and other symptoms associated with irritable bowel syndrome (IBS)
- Reduce blood pressure and regulate blood flow
- Enhance the body’s immune system and ability to fight infection
- Control nausea and vomiting caused by chemotherapy
- Reduce the intensity or frequency of migraine headaches in children and teenagers
- Treat and ease the symptoms of asthma
- Hasten the healing of some skin diseases
- Improve psoriasis and atopic dermatitis
- Change negative behaviors, such as smoking, bedwetting and overeating
- Reduce fear, stress and anxiety
- Eliminate or decrease the intensity of phobias
- A typical session lasts from 30 to 60 minutes.
- The number of sessions can range from one to a series of several.
- You generally bring yourself out of hypnosis at the end of a session.
- You can usually resume your daily activities immediately after a session.
Although hypnosis may have the potential to help with a wide variety of conditions, it’s not a magic bullet. It’s typically used as one part of a broader treatment plan rather than as a stand-alone therapy. Like any other therapy, it can be very helpful to some people and fail with others. It seems to work best when you’re highly motivated and your therapist is well trained and understands your particular problem.
A variety of hypnotic techniques exists. The approach you choose depends on what you want to accomplish, as well as your personal preferences. Your hypnotherapist may make a recommendation regarding the best technique for your particular situation.
For example, in one method, a hypnotherapist leads you into hypnosis by talking in gentle, soothing tones and describing images that create a sense of relaxation, security and well-being. While you’re under hypnosis, the hypnotherapist suggests ways for you to achieve specific goals — for example, reducing pain or stress or helping to eliminate the cravings associated with smoking cessation.
In another technique, once you’re under hypnosis the hypnotherapist helps stimulate your imagination by suggesting specific mental images to see in your mind’s eye. This conscious creation of vivid, meaningful pictures in your mind is called mental imagery, and it’s a powerful way to help bring about what you want to achieve. For example, hypnotherapists can help athletes specifically visualize what they want to accomplish before they perform it physically.
Self-hypnosis is a third technique. A certified hypnotherapist needs to teach you how to induce a state of hypnosis in yourself. You then can use this skill to help yourself.
Although hypnotherapists, like other health care practitioners, each have their own style, expect some common elements:
Myths About Hypnosis
If you’ve ever seen a “hypnotist” who uses trance states as entertainment in a stage act, you’ve probably witnessed several of the myths about hypnosis in action. Legitimate clinical hypnotherapy practiced by a qualified professional is not the same process as that performed on stage.
Myth: When you’re under hypnosis, you surrender your free will. Reality: Hypnosis is a heightened state of concentration and focused attention. When you’re under hypnosis, you don’t lose your personality, your free will or your personal strength.
Myth: When you’re under hypnosis, the hypnotherapist controls you. Reality: You do hypnosis voluntarily for yourself. A hypnotherapist only serves as a knowledgeable guide or facilitator.
Myth: Under hypnosis, you lose consciousness and have amnesia. Reality: A small number of people who go into a very deep hypnotic state experience spontaneous amnesia. However, most people remember everything that occurs under hypnosis.
Myth: You can be put under hypnosis without your consent. Reality: Successful hypnosis depends on your willingness to experience it. Even with voluntary participation, not everyone can be led into a hypnotic state.
How Hypnosis Induced Paralysis Can Teach Us How the Brain Works
FRIDAY
JUL 31, 2009
The June 2009 issue of the Journal Neuron just published a fascinating study that could be the next step towards figuring out how hypnosis actually works in the brain.
As you probably know, I am big into brain science – and especially studies employing functional magnetic resonance imaging (fMRI). What I like about fMRI is that it provides a window into the brain; allowing scientists to find out what is really going on as opposed to solely relying on reporting or behavioral assessments.
I wish they had this technology when I was in graduate school in the mid 90’s – I never would have left.
Anyway, let’s take you through the experiment. I think you will find this interesting and maybe even helpful in some strange way.
The Study
Researchers recruited 18 healthy volunteers, and asked them to perform a “go-no go” task while their brains were being watched via fMRI.
The participants were first required to fixate on a cross which was shown for half a second. This was followed by a grayscale picture of either a left or a right hand; this was a cue shown to indicate which hand was at play.
After an interval of 1-5 seconds, the hand changed color.
If it turned green, they had to respond, as quickly as possible, by pressing a button with the corresponding hand.
If it turned red, they were to withhold the prepared movement and do nothing.
Here is the Fun Part!
Twelve of the participants played the game both under hypnosis (and told that their left hand was paralyzed), or in a normal state.
6 of the participants performed the task while feigning paralysis (acting “as if” they were unable to move the fingers of the left hand).
Both the control group (the group that feigned paralysis and the hypnosis group were able to resist pushing the button with the left hand – but the brain scans showed that the mechanisms involved were completely different!
This alone blows away the hypothesis that there is no difference between hypnosis and just acting. The evidence against this theory is more than compelling, but it is nice to see this happening in the brain itself.
More about The Test (and why science is so cool)
There were two tests going on here.
First, they were testing how the hypnosis paralysis group suppressed the movement:
It either suppressed the movement in the preparatory level (by not “gearing up” the left hand when the grey left was displayed).
OR
It suppressed the movement after the preparatory level (meaning the brain recognized the left hand and it geared up, but just didn’t allow the left hand to move.
Second (and what is really interesting to me)
By comparing the brain activity measured during hypnosis and in the feigned paralysis group, they could see whether the mechanisms in the brain were similar.
Test One Results – It is Not about the Planning
The results of the first test were pretty interesting. It turns out that when the hypnosis group was shown the grey left hand, that there was in fact brain activity in the right motor cortex which is associated with planning to execute a necessary command on the left side of your body.
In fact in both the hypnosis group and the feigned paralysis group, both group’s brains planned and/or “got ready” to move the left hand. This was true of all the subjects regardless of whether they were not hypnotized or just pretending.
So the answer to the first test is that the preparatory part of the brain is NOT blocked, it happens after preparation.
Test Two Results: Why Hypnosis is not like Pretending
The next step was examining the activity of the motor cortex at the time of actual hand movement execution.
At the time when the movement should be executed, the normal group again showed activity in the right motor cortex, but the hypnotized group did not (kind of expected since they did not move their left paralyzed hand).

However, the hypnotized group did show increased activity in the prefrontal and parietal cortexes (these are involved in executive control and attention). More relevant, there was also increased activity in a part of the brain called the precuneus.
The precuneus is involved in mental imagery and especially in making representations of self (it is heavily involved in creating your self-image).
In the feigning or “pretending” group, these areas of the brain did not experience more activity. Instead, there was increased activity in the right inferior frontal gyrus, which is involved in motor inhibition. (The hypnosis group did NOT experience increased activity in this area).
So What Does this Mean?
Sorry for all the brain talk (don’t worry; I have to refer to charts as well). And of course it is not wise to jump to conclusions. But, this not only shows a difference between pretending and hypnosis – it indicates that hypnosis uses internal representations and self imagery to take control of your behaviors – while “pretending” relies on will power.
Instructions given under hypnosis seem have the ability to override habitual action, without conscious awareness. And it seems to do so by working at the level of self image. This is why it is such a powerful tool for self-change.
The author of the study, Dr. Yann Cojan, said it differently, “These results suggest that hypnosis may enhance self-monitoring processes to allow internal representations generated by the suggestion to guide behavior but does not act through direct motor inhibition,” says Dr. Cojan.
Here is my two cents. Having been “hypnotized” more times than I can count, and talking to our customer base (full disclosure - my company sells hypnosis CDs), the results make sense.
When folks use hypnosis for weight loss, for example, they report that when they go to the fridge to get a snack – it is almost as if something pulls them away from this action. It seems like as the self image is built, it gets in the way of behaviors that were causing you trouble. And this is without a person having to think about it, or use will power.
Anyway, there is still a lot to learn!
I am very interested in what you think about this article, and would love to start a good conversation about brain science and behavior in general.
Please comment and sign up for Intense Debates. I promise to answer any questions on the blog. My answers are usually replies to specific posts.
Just click the blue “reply” by any comment to see my response.
*Source:
The Brain under Self-Control: Modulation of Inhibitory and Monitoring Cortical Networks during Hypnotic Paralysis
Neuron, Volume 62, Issue 6, 25 June 2009, Pages 862-875
Yann Cojan, Lakshmi Waber, Sophie Schwartz, Laurent Rossier, Alain Forster and Patrik Vuilleumier
Brain Imaging
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Removing Part of Skull Makes for Better Brain Scans By Tia Ghose Removing a chunk of the skull can make way for stronger, clearer signals from a common method of monitoring brainwaves. The skull-free electroencephalography could make neural prostheses like bionic arms or eyes less invasive. “It’s notoriously hard to have a long-term electrode implanted in the brain,” said University of California at Berkeley neuroscientist Bradley Voytek, lead author of the study to be published in a forthcoming issue of the Journal of Cognitive Neuroscience. So if you can get around that by just having a small hole drilled into the skull, that would be very helpful.” Doctors sometimes treat patients who have suffered severe head trauma, such as gunshot or knife wounds, with what is known as a hemicraniectomy. A surgeon cuts out a chunk of skull that’s the diameter of an orange or grapefruit, to give the brain room to swell. Surgeons usually reattach the piece of bone four to six months later, once the swelling has subsided and the skin has healed. In the meantime, the patient’s scalp and a helmet protect the exposed area. And doctors stitch the skull fragment into the abdomen, “bathed in the body’s own fluids,” to prevent it from deteriorating, Voytek said. Voytek’s team took advantage of this brief window of time to compare EEG signals from people with and without the skull as a barrier. Patients performed simple tasks like squeezing a person’s hand or listening to an “oddball stimulus” of three low-pitched sounds followed by a higher one, he said. Wired.com © 2009 Condé Nast Digital.
See also: Chapter 2: Functional Neuroanatomy: The Nervous System and Behavior; Chapter 3: Neurophysiology: Conduction, Transmission, and the Integration of Neural Signals
Posted: 01.25.2010 Conditional Consciousness: Predicting Recovery from the Vegetative State By Katherine Harmon In patients who have survived severe brain damage, judging the level of actual awareness has proved a difficult process. And the prognosis can sometimes mean the difference between life and death. New research suggests that some vegetative patients are capable of simple learning—a sign of consciousness in many who had failed other traditional cognitive tests. To determine whether patients are in a minimally conscious state (in which there is some evidence of perception or intentional movement) or have sunk into a vegetative state (in which neither exists), doctors have traditionally used a battery of tests and observations. Many of them require some subjective interpretation, such as deciding whether a patient’s movements are purposeful or just random. “We want to have an objective way of knowing whether the other person has consciousness or not,” says Mariano Sigman, who directs the Integrative Neuroscience Laboratory at the University of Buenos Aires. That desire stems in part from surprising neuroimaging work that showed that some vegetative patients, when asked to imagine performing physical tasks such as playing tennis, still had activity in premotor areas of their brains. In others, verbal cues sparked language sectors. A recent study found that about 40 percent of vegetative state diagnoses are incorrect. To explore possible tests of consciousness in patients, Sigman and his colleagues turned to classical conditioning: they sounded a tone and then sent a light puff of air to the patient’s eye. The air puff would cause a patient to blink or flinch the eye, but after repeated trials over half an hour, many patients would begin to anticipate the puff, blinking an eye after only hearing the tone. © 1996-2009 Scientific American Inc.
See also: Chapter 2: Functional Neuroanatomy: The Nervous System and Behavior; Chapter 19: Language and Cognition
Posted: 12.17.2009 By Laura Sanders The 18-inch-long Atlantic salmon lay perfectly still for its brain scan. Emotional pictures —a triumphant young girl just out of a somersault, a distressed waiter who had just dropped a plate — flashed in front of the fish as a scientist read the standard instruction script aloud. The hulking machine clunked and whirred, capturing minute changes in the salmon’s brain as it assessed the images. Millions of data points capturing the fluctuations in brain activity streamed into a powerful computer, which performed herculean number crunching, sorting out which data to pay attention to and which to ignore. By the end of the experiment, neuroscientist Craig Bennett and his colleagues at Dartmouth College could clearly discern in the scan of the salmon’s brain a beautiful, red-hot area of activity that lit up during emotional scenes. An Atlantic salmon that responded to human emotions would have been an astounding discovery, guaranteeing publication in a top-tier journal and a life of scientific glory for the researchers. Except for one thing. The fish was dead. The scanning technique used on the salmon — called functional magnetic resonance imaging — allows scientists to view the innards of a working brain, presumably reading the ebbs and flows of activity that underlie almost everything the brain does. Over the last two decades, fMRI has transformed neuroscience, enabling experiments that researchers once could only dream of. With fMRI, scientists claim to have found the brain regions responsible for musical ability, schadenfreude, Coca-Cola or Pepsi preference, fairness and even tennis skill, among many other highly publicized conclusions. © Society for Science & the Public 2000 - 2009
See also: Chapter 2: Functional Neuroanatomy: The Nervous System and Behavior
Posted: 12.05.2009 Courtroom First: Brain Scan Used in Murder Sentencing By Alexis Madrigal Email Author A defendant’s fMRI brain scan has been used in court for what is believed to be the first time. Brain scan evidence that the defense claimed shows the defendant’s brain was psychopathic was allowed into the sentencing portion of a murder trial in Chicago, Science reported Monday. Brian Dugan, who had been convicted of the rape and murder of a 10-year old, was sentenced to death, despite the fMRI scans. “I don’t know of any other cases where fMRI was used in that context,” Stanford professor Hank Greely told Science. While the possibility of using fMRI data in a variety of contexts, particularly lie detection, has bounced around the margins of the legal system for years, there are almost no documented cases of its actual use. In the 2005 case Roper v. Simmons, the Supreme Court allowed brain scans to be entered as evidence to show that adolescent brains work differently than adult brains. That’s a far cry, though, from using fMRI to establish the truth of testimony or that specific structures within an individual defendant’s brain are legally relevant. It’s difficult to tell whether the Dugan case will be a watershed moment in the use of brain scan evidence in court, or if the evidence impacted the decision in this case. © 2009 Condé Nast Digital.
See also: Chapter 2: Functional Neuroanatomy: The Nervous System and Behavior; Chapter 15: Emotions, Aggression, and Stress
Posted: 11.27.2009 By R. Douglas Fields Practice makes perfect, but how? Two groups of neuroscientists using MRI brain imaging announced last month that they were able to see changes inside the brains of people after mastering a new skill. The big surprise is that the part of the brain that changed has no neurons or synapses in it! The cerebral remodeling during learning was seen in the mysterious and still largely unexplored “white matter” region of the brain. “Grey matter” is synonymous with smarts, but in fact only half of the human brain is grey matter. White matter, the “other brain tissue”, is rarely mentioned. Neurons in the cerebral cortex are packed into in the top layers of the brain, where they are connected together through synapses. Learning takes place in the grey matter by linking neurons together into new circuits by strengthening synapses or forming new ones. But beneath the topsoil of the brain lies a dense network of fibers packed into a spaghetti-like snarl that is so complicated it is difficult to study or comprehend. These fibers are the wire-like axons projecting out from neurons in grey matter that transmit electrical impulses. Like buried telephone lines, these tightly bundled cables transmit information over long distances to communicate between distant regions of the cerebral cortex that are specialized to carry out different aspects of a complex cognitive function. © 1996-2009 Scientific American Inc.
See also: Chapter 17: Learning and Memory: Biological Perspectives; Chapter 2: Functional Neuroanatomy: The Nervous System and Behavior
Posted: 11.27.2009 Shedding light on how the brain works By By Carolyn Y. Johnson More than two centuries ago, the Italian scientist Luigi Galvani found that electricity could make a dead frog’s leg kick, as if it were alive. Today, using the same basic principle but new tools, scientists are employing light to trigger brain cells - looking not for a kick, but for the origins of emotions, behaviors, and diseases in the brain. Advanced imaging technologies have given neuroscientists new ways to peer into the working mind, but a precise understanding of how 100 billion brain cells create everything from memories to mental illness has remained elusive. Now, by using gene therapy to insert light-sensitive proteins from algae and other organisms into brain cells, scientists are able to control specific brain circuits with light, and then watch what happens. It’s a big shift, said Dr. Karl Deisseroth, a neuroscientist and psychiatrist at Stanford University, who compares the difference between imaging the brain and triggering individual cells to learning the rules of football by watching the game on a high-end TV or by controlling players. “It wouldn’t matter how good your video camera was or your TV was; it would still be very mysterious, and that’s imaging,’’ Deisseroth said. The new technology, on the other hand, “allows you to play the role of coach and understand things.’’ © 2009 NY Times Co.
See also: Chapter 2: Functional Neuroanatomy: The Nervous System and Behavior; Chapter 7: Life-Span Development of the Brain and Behavior
Posted: 11.24.2009 By Nick Higham For an actor, the performance conditions weren’t exactly ideal: flat on her back in a large machine, under strict instructions to lie as still as possible, speaking in short bursts interspersed with the shrill sound of a magnetic resonance imaging scanner. But last week Fiona Shaw, one of Britain’s leading actresses - who has in her time played everything from the tragic heroine Medea to Shakespeare’s Richard II - volunteered in the cause of science to spend an hour having her brain scanned while “acting”. Professor Sophie Scott of the Institute of Cognitive Neuroscience at University College London wanted to know what happens physically in an actor’s head when they pretend to be someone else. She hoped that scanning Fiona’s brain in action would be able to tell us. The scanner works by measuring blood flow to different parts of the brain. The harder a part is working, the more blood flows into it. The parts of the brain that control speech are well known: what Prof Scott wanted to know was whether other parts of the brain would also “light up” when actors speak in character rather than as themselves. The results of the experiment will be on display as part of the Wellcome Collection’s new exhibition on identity. Prof Scott, who is also a Wellcome senior fellow, says our speech and the way we use language are important components of our identity - and one of the ways actors seek to convince their audience that they are another person is of course by changing their voice. For the experiment, Fiona Shaw performed snatches of T S Eliot’s poem The Waste Land. (Appropriately enough, given the circumstances, Eliot’s original title for the poem was He Do the Police in Different Voices.) (C)BBC
See also: Chapter 2: Functional Neuroanatomy: The Nervous System and Behavior
Posted: 11.24.2009 Hypnosis has ‘real’ brain effect Hypnosis has a “very real” effect that can be picked up on brain scans, say Hull University researchers. An imaging study of hypnotised participants showed decreased activity in the parts of the brain linked with daydreaming or letting the mind wander. The same brain patterns were absent in people who had the tests but who were not susceptible to being hypnotised. One psychologist said the study backed the theory that hypnosis “primes” the brain to be open to suggestion. Hypnosis is increasingly being used to help people stop smoking or lose weight and advisers recently recommended its use on the NHS to treat irritable bowel syndrome. It is not the first time researchers have tried to use imaging studies to monitor brain activity in people under hypnosis. But the Hull team said these had been done while people had been asked to carry out tasks, so it was not clear whether the changes in the brain were due to the act of doing the task or an effect of hypnosis. In the latest study, the team first tested how people responded to hypnosis and selected 10 individuals who were “highly suggestible” and seven people who did not really respond to the technique other than becoming more relaxed. The participants were asked to do a task under hypnosis, such as listening to non-existent music, but unknown to them the brain activity was being monitored in the rest periods in between tasks, the team reported in the journal Consciousness and Cognition. In the “highly suggestible” group there was decreased activity in the part of the brain involved in daydreaming or letting the mind wander - also known as the “default mode” network. BBC © MMIX
See also: Chapter 19: Language and Cognition; Chapter 2: Functional Neuroanatomy: The Nervous System and Behavior
Posted: 11.16.2009 Signature of consciousness captured in brain scans by Anil Ananthaswamy A telltale signature of consciousness has been detected that takes us a step closer to disentangling the brain activity underlying conscious and unconscious brain processes. It turns out that there is a similar pattern of neural activity each time we become conscious of the same picture, but not if we process information from the image unconsciously. These contrasting patterns of activity can now be detected via brain scans, and could one day help determine if patients with brain damage are conscious. They might even be used to probe consciousness in animals. “It’s very exciting work,” says neuroscientist Raphaël Gaillard of the University of Cambridge, who was not involved in the work. “The use of a reproducibility measure to disentangle conscious and non-conscious processes is genuinely new.” Gaillard has previously shown that coordinated activity across the entire brain is one of the signatures of consciousness . Consistent signals So far, efforts to find a brain signature of consciousness have focused on the intensity of neural activity, how long it lasts, and whether signals tend to be synchronised across different regions of the brain. “We were looking for something other than the intensity and duration of the neural activity that characterises conscious neural processing,” says Aaron Schurger of Princeton University in New Jersey, who led the new work. © Copyright Reed Business Information Ltd.
See also: Chapter 19: Language and Cognition; Chapter 2: Functional Neuroanatomy: The Nervous System and Behavior
Posted: 11.13.2009 Head-mounted microscope sees brain beneath the skull A small microscope that can be mounted on an animal’s head should offer a front-row view of how its brain processes visual and other stimuli on the move. A laser inside the device scans the activity of neurons through a tiny hole in the skull, made prior to the experiment under anaesthetic. When the microscope was attached to freely moving rats looking at screens, it produced images of brain cells that had been labelled with a fluorescent dye. Compared with previous methods – which require restraining animals and inserting electrodes – this technique is much less invasive, revealing brain activity in animals that are moving and interacting with their environment in a more natural way. It was developed at the Max Planck Institute for Biological Cybernetics in Tübingen, Germany. Journal reference: Proceedings of the National Academy of Sciences, DOI: 10.1073/pnas.0903680106 © Copyright Reed Business Information Ltd.
See also: Chapter 2: Functional Neuroanatomy: The Nervous System and Behavior
Posted: 11.10.2009 Brain scanners can tell what you’re thinking about by Ewen Callaway, Chicago WHAT are you thinking about? Which memory are you reliving right now? You may think that only you can answer, but by combining brain scans with pattern-detection software, neuroscientists are prying open a window into the human mind. In the last few years, patterns in brain activity have been used to successfully predict what pictures people are looking at, their location in a virtual environment or a decision they are poised to make. The most recent results show that researchers can now recreate moving images that volunteers are viewing - and even make educated guesses at which event they are remembering. Last week at the Society for Neuroscience meeting in Chicago, Jack Gallant, a leading “neural decoder” at the University of California, Berkeley, presented one of the field’s most impressive results yet. He and colleague Shinji Nishimoto showed that they could create a crude reproduction of a movie clip that someone was watching just by viewing their brain activity. Others at the same meeting claimed that such neural decoding could be used to read memories and future plans - and even to diagnose eating disorders. Understandably, such developments are raising concerns about “mind reading” technologies, which might be exploited by advertisers or oppressive governments (see “The risks of open-mindedness”). Yet despite - or perhaps because of - the recent progress in the field, most researchers are wary of calling their work mind-reading. Emphasising its limitations, they call it neural decoding. © Copyright Reed Business Information Ltd
See also: Chapter 2: Functional Neuroanatomy: The Nervous System and Behavior
Posted: 10.29.2009 The Root of Thought: What Do Glial Cells Do? By Andrew Koob Andrew Koob received his Ph.D. in neuroscience from Purdue University in 2005, and has held research positions at Dartmouth College, the University of California, San Diego, and the University of Munich, Germany. He’s also the author of The Root of Thought, which explores the purpose and function of glial cells, the most abundant cell type in the brain. Mind Matters editor Jonah Lehrer chats with Koob about why glia have been overlooked for centuries, and how new experiments with glial cells shed light on some of the most mysterious aspects of the mind. LEHRER: Your new book, The Root of Thought, is all about the power of glial cells, which actually make up nearly 90 percent of cells in the brain. What do glial cells do? And why do we have so many inside our head? KOOB: Originally, scientists didn’t think they did anything. Until the last 20 years, brain scientists believed neurons communicated to each other, represented our thoughts, and that glia were kind of like stucco and mortar holding the house together. They were considered simple insulators for neuron communication. There are a few types of glial cells, but recently scientists have begun to focus on a particular type of glial cell called the ‘astrocyte,’ as they are abundant in the cortex. Interestingly, as you go up the evolutionary ladder, astrocytes in the cortex increase in size and number, with humans having the most astrocytes and also the biggest. Scientists have also discovered that astrocytes communicate to themselves in the cortex and are also capable of sending information to neurons. Finally, astrocytes are also the adult stem cell in the brain and control blood flow to regions of brain activity. Because of all these important properties, and since the cortex is believed responsible for higher thought, scientists have started to realize that astrocytes must contribute to thought. © 1996-2009 Scientific American Inc.
See also: Chapter 2: Functional Neuroanatomy: The Nervous System and Behavior; Chapter 19: Language and Cognition
Posted: 10.29.2009 Brain Scans Link ADHD To Biology By Katherine Ellison For decades, attention-deficit hyperactivity disorder has sparked debate. Is it a biological illness, the dangerous legacy of genes or environmental toxins, or a mere alibi for bratty kids, incompetent parents and a fraying social fabric? With 4.5 million U.S. children having received a diagnosis of the disorder — and more than half of them taking prescription drugs to control it — the question has divided doctors and patients, parents and teachers, and mothers and fathers. Scientists maintain that they’ve been narrowing in on the origins and mechanics of disabling distraction, while gathering increasing evidence that ADHD is as real as such less controversial disorders as Down syndrome and schizophrenia. Their most recent progress is described in a Sept. 9 report in the Journal of the American Medical Association, based on a new study that indicates a striking difference in the brain’s motivational machinery in people with ADHD symptoms. “This is another big piece in the puzzle saying that there is something there, that this is not simply a matter of anxious parents,” said James Swanson, a co-author of the report and a developmental psychologist based at the University of California at Irvine. The JAMA study said that, compared with a group of healthy subjects, brain scans of 53 adults with ADHD revealed a flaw in the way they process dopamine, which among other things, alerts people to new information and helps them anticipate pleasure and rewards. Swanson speculated that people with ADHD may even have a net deficit of dopamine. © 2009 The Washington Post Company
See also: Chapter 7: Life-Span Development of the Brain and Behavior; Chapter 2: Functional Neuroanatomy: The Nervous System and Behavior
Posted: 09.22.2009 Scanning Dead Salmon in fMRI Machine Highlights Risk of Red Herrings By Alexis Madrigal Email Author Neuroscientist Craig Bennett purchased a whole Atlantic salmon, took it to a lab at Dartmouth, and put it into an fMRI machine used to study the brain. The beautiful fish was to be the lab’s test object as they worked out some new methods. So, as the fish sat in the scanner, they showed it “a series of photographs depicting human individuals in social situations.” To maintain the rigor of the protocol (and perhaps because it was hilarious), the salmon, just like a human test subject, “was asked to determine what emotion the individual in the photo must have been experiencing.” The salmon, as Bennett’s poster on the test dryly notes, “was not alive at the time of scanning.” methodsIf that were all that had occurred, the salmon scanning would simply live on in Dartmouth lore as a “crowning achievement in terms of ridiculous objects to scan.” But the fish had a surprise in store. When they got around to analyzing the voxel (think: 3-D or “volumetric” pixel) data, the voxels representing the area where the salmon’s tiny brain sat showed evidence of activity. In the fMRI scan, it looked like the dead salmon was actually thinking about the pictures it had been shown. “By complete, random chance, we found some voxels that were significant that just happened to be in the fish’s brain,” Bennett said. “And if I were a ridiculous researcher, I’d say, ‘A dead salmon perceiving humans can tell their emotional state.’” © 2009 Condé Nast Digital.
See also: Chapter 2: Functional Neuroanatomy: The Nervous System and Behavior
Posted: 09.21.2009 Brain Scans for Schizophrenia? By Michael Torrice If you’re at risk for heart disease, doctors can monitor your cholesterol. But psychiatrists don’t have an analogous test for mental illnesses. That may change with a new discovery: Scientists have pinpointed a small spot in the brain that has a 71% chance of predicting whether high-risk patients will develop schizophrenia. About 75% of diagnosed schizophrenics show early, fleeting signs of the disease before they fully develop it. These so-called prodromal symptoms include mild hallucinations, such as hearing your name in the wind, or a sudden, unfounded suspicion that your friends are talking about you behind your back. Some patients may even experience a full psychotic episode–similar to what schizophrenics experience chronically–which lasts only a couple of days. Not all prodromal patients develop psychotic disorders: Two-and-a-half years after first experiencing these symptoms, only 35% receive a schizophrenia diagnosis. Predicting who gets that diagnosis is “a little better than flipping a coin,” says Scott Schobel, a psychiatrist at Columbia University. To help understand how these patients progress from mild hallucinations to schizophrenia, Schobel and his colleagues compared brain activity between 18 schizophrenic and 18 healthy patients. The scientists used a high-resolution version of functional magnetic resonance imaging, which measures brain activity through changes in blood volume, to take detailed snapshots of the subjects’ brains while they lay in the scanner. © 2009 American Association for the Advancement of Science.
See also: Chapter 16: Psychopathology: Biological Basis of Behavior Disorders; Chapter 2: Functional Neuroanatomy: The Nervous System and Behavior
Posted: 09.12.2009 The Dawning Age of Mind-Reading Machines By Hilmar Schmundt Imagine controlling machines, typing text or juggling balls using nothing but the power of thought. What sounds like far-fetched science fiction is gradually becoming possible, providing hope for disabled patients — and new gimmicks for the computer gaming industry. My original plan was to write this article with nothing but the power of thought, but the technology of transforming ideas into characters is still crude and prone to error. The first word alone took a few minutes, and even after that the result was still “diz” instead of “this.” Still, that little sentence is like a little miracle. The old dream of mind-reading is slowly becoming reality — though this time around it is the product of machines rather than the minds of fiction writers. “The advances are tremendous,” says Christoph Guger, the developer of a brain-reading system. “In the past, you would have had to train for days. Today, entering text takes only a few minutes.” Guger is an engineer and a businessman. But with his hair falling past his jacket’s collar, he looks the part of a start-up entrepreneur. Still, he is certainly not new to the business. His company, Guger Technologies, which is based in the Austrian city of Graz, has been a supplier to countless brain-research laboratories for years. In addition to scalpels and medications, though, Guger also sells thought-transport technology. © SPIEGEL ONLINE 2009
See also: Chapter 2: Functional Neuroanatomy: The Nervous System and Behavior; Chapter 1: Biological Psychology: Scope and Outlook
Posted: 08.29.2009 Michael L. Anderson Psychology generally approaches the study of the mind by starting with behavior, and trying to infer the hidden mechanisms that produce it. Neuroscience, in contrast, begins by examining the smallest, deepest parts of the mechanism–genes and neurons–and tries to determine which behaviors these help produce. Ideally, the “outside-in” and “bottom-up” approaches are complementary, but each suffers from some inherent limitations. In psychology, the trouble is that for every piece of observed behavior, there are innumerable mechanisms that could have produced it. Similarly, the neurosciences have been hampered by the dearth of technologies allowing them to observe the brain in action. Knowing how the brain’s smallest parts operate isn’t the same as knowing how those parts interact to generate behavior. Advanced imaging technologies have long promised to help bridge the gap between psychology and neuroscience by allowing us to peer “inside the box” and observe the living, working brain. Functional magnetic resonance imaging has been among the most important of these, but since fMRI doesn’t measure brain function directly–it detects changes in blood oxygenation levels from which we infer neural activity–it leaves us in roughly the same position as a psychologist observing behavior. But thanks to a new way of using MRI scanners to take a different kind of picture–a technique called Diffusion Tensor Imaging–things have just gotten a lot more interesting. By tracking the motion of water molecules in the brain, DTI allows you to see where nerve fibers lead and to map the fiber bundles wiring together various parts of the cortex. Such a map is called a “connectome.” 2009 Forbes.com LLC
See also: Chapter 2: Functional Neuroanatomy: The Nervous System and Behavior
Posted: 08.27.2009 Many degrees of separation in dementia brains by Celeste Biever YOU might expect the brain of someone with a mental disorder to be disorganised. But it’s the nature of the disorganisation that’s important - a finding that one day could help early diagnosis of different types of dementia. We already know that the different regions of healthy brains are linked in a so-called small-world network, which makes communication very efficient. For people with Alzheimer’s or other types of dementia, however, it’s a different story. In small-world networks - which also emerge, for example, in social networks - each node is connected to a lot of nearby nodes, but also has a few links to distant ones. Because of this, any node can communicate with almost any other in just a few hops. This may explain the brain’s formidable ability to process masses of information rapidly. “A small world, in theoretical terms, is the optimal network,” says Willem de Haan of the VU University Medical Center in Amsterdam, the Netherlands. De Haan’s team used scalp electrodes to measure the brain activity of resting volunteers, of whom 20 had mild to moderate Alzheimer’s, 15 had a rare form of dementia called frontal temporal lobe dementia (FTLD), and 23 were healthy. The researchers figured out the underlying network structure of the volunteers’ brains from the electrical activity in different regions over time. © Copyright Reed Business Information Ltd.
See also: Chapter 7: Life-Span Development of the Brain and Behavior
Posted: 08.27.2009 Are the Brains of Reckless Teens More Mature Than Those of Their Prudent Peers? By Robert Epstein and Jennifer Ong Thrill seeking and poor judgment go hand in hand when it comes to teenagers—an inevitable part of human development determined by properties of a growing but immature brain. Right? Not so fast. A study being published tomorrow turns that thinking upside down: The brains of teens who behave dangerously are more like adult brains than are those of their more cautious peers. Psychologists have long believed that the brain’s judgment-control systems develop more slowly than emotion-governing systems, not maturing until people are in their mid-20s. Hence, teens end up taking far more risks than adults do. Evidence supporting this idea comes from studies looking at functional and structural properties of gray matter, the important part of the brain that contains the neurons that relay brain signals. At least two observations undermine this theory, however. First, American-style teen turmoil is absent in more than 100 cultures around the world, suggesting that such mayhem is not biologically inevitable. Second, the brain itself changes in response to experiences, raising the question of whether adolescent brain characteristics are the cause of teen tumult or rather the result of lifestyle and experiences. Because brain research is virtually always correlational in design, determining whether brain properties are causes or effects is impossible. Now neuroscientists Gregory S. Berns, Sara Moore and Monica Capra of Emory University suggest that teen risk-taking is associated not with an immature brain but with a mature, adultlike brain—exactly the opposite of conventional wisdom. © 1996-2009 Scientific American Inc.
See also: Chapter 7: Life-Span Development of the Brain and Behavior; Chapter 2: Functional Neuroanatomy: The Nervous System and Behavior
Posted: 08.27.2009 Expanding waistlines may cause shrinking brains by Nora Schultz BRAIN regions key to cognition are smaller in older people who are obese compared with their leaner peers, making their brains look up to 16 years older than their true age. As brain shrinkage is linked to dementia, this adds weight to the suspicion that piling on the pounds may up a person’s risk of the brain condition. The brains of elderly obese people looked 16 years older than the brains of those who were lean Previous studies suggested that obesity in middle age increases the risk of dementia decades later, which is accompanied by increased brain shrinkage compared with leaner people. Now brain scans of older people have revealed the areas that are hardest hit, as well as the full extent of brain size differences between obese people and those of average weight. From brain scans initially carried out for a different study, Paul Thompson from the University of California in Los Angeles and colleagues selected 94 from people in their 70s who were still “cognitively normal” five years after the scan. This was to exclude people with disorders that might have confused the results. The researchers then transformed these scans into detailed three-dimensional maps. People with higher body mass indexes had smaller brains on average, with the frontal and temporal lobes - important for planning and memory, respectively - particularly affected (Human Brain Mapping, DOI: 10.1002/hbm.20870). While no one knows whether these people are more likely to develop dementia, a smaller brain is indicative of destructive processes that can develop into dementia. © Copyright Reed Business Information Ltd
See also: Chapter 13: Homeostasis: Active Regulation of Internal States; Chapter 19: Language and Cognition
Posted: 08.24.2009 |
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Brain Scans Show Hypnosis Has Real Effect on the Brain
16th Nov 2009
Hypnosis has a “very real” effect that can be picked up on brain scans, say Hull University researchers.
An imaging study of hypnotised participants showed decreased activity in the parts of the brain linked with daydreaming or letting the mind wander.
The same brain patterns were absent in people who had the tests but who were not susceptible to being hypnotised.
One psychologist said the study backed the theory that hypnosis “primes” the brain to be open to suggestion.
Hypnosis is increasingly being used to help people stop smoking or lose weight and advisers recently recommended its use on the NHS to treat irritable bowel syndrome.
This shows that the changes were due to hypnosis and not just simple relaxation
Dr William McGeown, study leader
It is not the first time researchers have tried to use imaging studies to monitor brain activity in people under hypnosis.
But the Hull team said these had been done while people had been asked to carry out tasks, so it was not clear whether the changes in the brain were due to the act of doing the task or an effect of hypnosis.
In the latest study, the team first tested how people responded to hypnosis and selected 10 individuals who were “highly suggestible” and seven people who did not really respond to the technique other than becoming more relaxed.
The participants were asked to do a task under hypnosis, such as listening to non-existent music, but unknown to them the brain activity was being monitored in the rest periods in between tasks, the team reported in the journal Consciousness and Cognition.
Default mode
In the “highly suggestible” group there was decreased activity in the part of the brain involved in daydreaming or letting the mind wander - also known as the “default mode” network.
One suggestion of how hypnosis works, supported by the results, is that shutting off this activity leaves the brain free to concentrate on other tasks.
Study leader Dr William McGeown, a lecturer in the department of psychology, said the results were unequivocal because they only occurred in the highly suggestible subjects…..MORE
Learning in trance
Abstract
This study examined the fundamental question, whether verbal memory processing in hypnosis and in the waking state is mediated by a common neural system or by distinct cortical areas. Seven right-handed volunteers (25.4 years, sd 3.1) with high-hypnotic susceptibility scores were PET-scanned while encoding/retrieving word associations either in hypnosis or in the waking state. Word-pairs were visually presented and highly imaginable, but not semantically related (e.g. monkey-street). The presentation of pseudo-words served as a reference condition. An emission scan was recorded after each intravenous administration of O-15 water. Encoding under hypnosis was associated with more pronounced bilateral activations in the occipital cortex and the prefrontal areas as compared to learning in the waking state. During memory retrieval of word-pairs which had been previously learned under hypnosis, activations were found in the occipital lobe and the cerebellum. Under both experimental conditions precuneus and prefrontal cortex showed a consistent bilateral activation which was most distinct when the learning had taken place under hypnosis.
In order to further analyze the effect of hypnosis on imagery-mediated learning, we administered sets of high-imagery word-pairs and sets of abstract words. In the first experimental condition word-pair associations were presented visually. In the second condition it was found that highly hypnotisable persons recalled significantly more high-imagery words under hypnosis as compared to low-hypnotisables both in the visual and auditory modality. Furthermore, high-imagery words were also better recalled by the highly hypnotisable subjects during the non-hypnotic condition. The memory effect was consistently present under both, immediate and delayed recall conditions. Taken together, the findings advance our understanding of the neural representation that underlies hypnosis and the neuropsychological correlates of hypnotic susceptibility.
Keywords: Hypnosis; Positron emission tomography; Paired word association learning; Occipital cortex; Prefrontal cortex
Article Outline
- 1. Introduction
- 2. Experiment 1: Visual word-pair association learning
- 2.1. Methods
- 2.1.1. Experimental subjects
- 2.1.2. Positron emission tomography imaging
- 2.1.3. Experimental set-up: word-pair association learning
- 2.1.4. Analysis of data
- 2.2. Results
- 2.3. Conclusion
- 3. Experiment 2: Auditory word-pair association learning
- 3.1. Introduction
- 3.2. Preliminary test: methods
- 3.2.1. Experimental subjects
- 3.2.2. Experimental set-up
- 3.3. Main study: methods
- 3.3.1. Experimental subjects
- 3.3.2. Experimental set-up
- 3.4. Results
- 3.4.1. Immediate reproduction
- 3.4.1.1. High-imagery word-pair associations
- 3.4.1.2. Abstract word-pair associations
- 3.4.2. Delayed reproduction
- 3.5. Conclusion
- 4. Discussion
- 4.1. PET study
- 4.2. Behavioural studies
- References
The World Within: Part 3
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Hypnosis and Sex
by Brandon M in Spirituality, January 18, 2009
Find out how to open yourself up sexually, experience orgasm more fully, and attract people towards you. Become vibrant, alive and sexual with the power of your sub-conscious mind.
Since you are here, you probably already know about hypnosis. You know that it’s not some mystical state where the hypnotist has control over your will. You also probably know that when you are under hypnosis, you find yourself in a deep state of relaxation, and find that you are always aware of your surroundings. But how can hypnosis help your sex life? By using certain techniques with self-hypnosis, you can turn yourself into a vibrant love machine, and attract and initiate amazing, romantic adventures.
Hypnosis and Orgasm
It has been shown that under hypnosis, a man or woman can have a complete orgasm, without andphysical contact whatsoever! If the mind, the great super-computer, is able to stimulate such pleasure without anyone helping the process along, imagine what hypnosis might do to help you have better orgasms with your partner!
One thing that you can do is put yourself under trance. You do this by relaxing all the muscles in your body, count backwards or imagine yourself descending (tunnel, stairway, floating down on a cloud, etc.). This will help deepen the hypnotic, relaxed state. Once you are fully relaxed, you are able to bypass the critical mind and then send messages to the subconscious mind, which are accepted with no hesitation.
After you are under trance, imagine you and your partner having the most amazing, colorful, vibrant, powerful sex you have ever had. Both of you together, creating heat and energy, wrapping each other in the amazing life force and intimate pleasure. Feel your skin touching your partner’s skin, and put yourself in that visualization. Incorporate all your senses. Then imagine yourself having orgasm, and you react with the utmost excitement and pleasure that it absolutely floors you. Imagine it lasting as lone as you want it to, and perhaps imagining colors or lights going of on your brain. As the orgasm intensifies, imagine those colors and lights getting brighter, bigger, fuller. Keep imagining, then let go.
Once you and your partner (in real life) are having sex, whenever you are ready to orgasm, imagine those colors and light in your mind. Imagine them getting bigger, brighter, fuller. Let yourself go, imagining those colors and lights becoming brighter, fuller, bigger! Intensify this imagination! You won’t be disappointed in the few minutes you spent reprogramming your brain.
Become a Super-Sexy, Attractive You
There are many times when a person is not attracted to another because of their looks, but because of the energy they present. The person who supplies the world with electrifying, powerful, happy, sexy energy will attract more people than the person who has no energy to give. By reprogramming your mind, every day you can begin bringing more energy to your body and your life, thus attracting more people.
Did you know that the electromagnetic waves emitted from the heart are up to sixty times more than the brain? By creating an atmosphere of loving thoughts, images and feelings in your brain, this translates to your heart, enlightening your energy, giving a boost to the electricity you are emitting to potential lovers.
Go under trance and imagine loving thoughts and images. Feel how you feel when you see those images of love and peace and contentment. Incorporate all your sense in this visualization. Imagine yourself touching your future lover, kissing, taste, sense of smell, hearing your lover’s voice, looking into the eyes of your lover, feeling pure power and pulses of love.
Now while under this loving state of trance, instruct your brain and heart to send out waves of love to anyone and everyone around you. Let your mind and your heart attract friends and lovers to you easily, quickly. Imagine this happening. By imagining, instructing, feeling, and incorporating all your senses under hypnosis, your brain and body will do everything it can to support that visualization, and eventually bring your wishes into fruition.
You can bring love into your life. You can super charge your sex life. Are you ready to embrace your new, sexy, hypnotic life? Get ready.
Under The Knife, under hypnosis
“The surgeon was cutting and sewing inside me, but I could not feel any sensation at all”
“The hypnotic state is a normal state that everyone can access if they want to”
From issue 2511 of New Scientist magazine, 06 August 2005, page 34
Posted: Tue - August 30, 2005 at 11:33 PM Science Related Brain OtBot Previous Next
The mesmerized mind: scientists are unveiling how the brain works when hypnotized.
Mention hypnosis, and the image that springs to mind is a caped magician swinging a pocket watch, seducing otherwise sensible people into barking like dogs.
But hypnosis is more than a stage show act. For years, psychologists have used it to help patients calm preflight jitters, get a good night’s sleep or chuck a cigarette habit. Hypnosis even has uses in mainstream medicine for reducing the side effects of cancer treatments and helping patients cope with pain. Some physicians routinely employ hypnosis as an adjunct to mainstream anesthesia to help block pain during surgery or childbirth.
Most recently, hypnosis has advanced from stage and clinic into the laboratory. It is now used as a research tool to temporarily create hallucinations, compulsions, delusions and certain types of seizures in the lab so that these phenomena can be investigated in detail..
Such studies may lead to more effective treatments for a number of psychiatric and neurological disorders, assert psychologists Peter W. Halligan and David Oakley in the June issue of Trends in Cognitive Sciences.
Other scientists, intrigued by the many practical uses of hypnosis, are striving to figure out how it works. Using the latest neuroimaging tools, these scientists are getting a look at what goes on in the hypnotized brain. The findings are mesmerizing.
When hypnotized people act on a hypnotic suggestion, they really do see, hear and feel differently, such research shows. When they’re told to see colors, for example, the color-processing parts of their brains light up–despite the absence of any real color in view. When they are told to envision color objects in black and white, these color-processing areas are less active. Other imaging studies show that hypnotically induced pain activates the same brain areas as “real” pain.
Still, questions remain, says Halligan, of Cardiff University in Wales, who has studied hypnosis for more than a decade. Scientists have yet to discover how hypnosis produces physiological changes. And some scientists question whether such changes are confined to hypnosis. Perhaps the patterns of brain activity seen during hypnosis can occur during everyday experiences when people are fully absorbed in an activity, some researchers say.
The real question, says Halligan, is whether hypnosis is a specific brain state that differs from any other.
“In other words, is there some sort of neural correlate, or biological marker, within the brain during a hypnotic trance?” he asks.
The answer so far, emerging from studies done during the past few years, is maybe. New research at the University of Geneva suggests that hypnosis alters neural activity by rerouting some of the usual connections between brain regions. Such neurological detours don’t happen when subjects merely imagine a scenario.
Changing your mind
Hypnosis got its start as a “miracle cure” in 1774, when physician Franz Mesmer found away, using ethereal music played on a glass harmonica, to induce a hypnotic trance in patients suffering from various unexplained medical problems. Though eventually discredited as a healer, Mesmer demonstrated that the mind could be manipulated by suggestion to produce an effect in the body. So powerful is this effect that the practice was resurrected in the 19th century, before the discovery of ether, to block pain during major surgeries.
In this mysterious state of mind, the brain is “quiet” focused and superattentive. People sometimes report feeling disconnected from their surroundings and lost in thought. During hypnosis, subjects are more open than usual to suggestions and have the ability to focus intensely on a specific thought, feeling or sensation.
Most adults, about two-thirds, are hypnotizable to some degree, though some people experience the effects of hypnosis more intensely than others do, says David Spiegel, a psychiatrist at Stanford University School of Medicine who uses hypnosis in his medical practice. Ten to 15 percent of adults are “highly hypnotizable,” he says, meaning they can experience dramatic changes in perception with hypnosis.
A person’s ability to become hypnotized is unrelated to intelligence, compliancy or gullibility, but may be linked to an ability to become deeply absorbed in activities such as reading listening to music or daydreaming. People who find themselves engrossed in a best seller even while the television is blaring, or swept away by a movie and losing track of time, are likely to be quite hypnotizable.
During hypnosis, the hypnotherapist tries to direct thoughts, feelings and behavior by instructing a person to concentrate on particular images or ideas. A typical session starts with some sort of induction procedure that helps the subject relax–say, counting down from 20 to one or mentally descending a set of stairs.
To produce a specific behavior or thought, the hypnotherapist will make suggestions targeted toward the goal. To reduce the pain of a medical procedure, for example, a hypnotherapist might invoke an image of pain being turned down like the volume on a radio.
Over the years, rigorously controlled studies have shown that hypnosis can also control blood pressure and even make warts go away. But because very few studies have attempted to find out how it works, some scientists are still skeptical of its power.
Critics suggest hypnosis is nothing more than playacting, with subjects trying to please the hypnotist. That skepticism has driven some researchers to take a hard look at what happens in the brain during hypnosis. Over the past few years, scientists have begun gathering evidence that hypnosis can indeed measurably change how the brain works.
In 2005, scientists at Weill Medical College of Cornell University in New York City used functional MRI to show how hypnotic suggestions can override “automatic” processes in the brain. When shown the names of colors printed in different colors of ink–for example, the word red printed in blue–subjects were instructed to name the ink color while ignoring the word.
Though this task may sound easy, it’s often difficult for people who can read because the tendency is to automatically read the word instead of naming the color. When told under hypnosis that the words would appear as gibberish, highly hypnotizable subjects were able to perform the task faster, and with fewer errors, than subjects who were less hypnotizable and therefore less likely to respond to suggestion.
The fMRI results were also striking. Highly hypnotizable participants showed less activity in a brain area called the anterior cingulate cortex, which is active when people are trying to sort out conflicting information from different sources, such as contradictory word names and colors. The study was published in the Proceedings of the National Academy of Sciences.
Going deeper
Scientists agree that there is a pattern or “orchestra” of brain activity during hypnosis. Halligan and his colleagues are working to figure out what this particular pattern might be, and which–if any–brain region serves as conductor. As part of a collaboration with psychiatrist Quinton Deeley of King’s College London, the researchers are looking at how patterns of brain activity in the induction phase–the countdown–prepare the brain for suggestions.
Preliminary findings suggest that hypnosis boosts activity in the brain’s prefrontal cortex–a region responsible for various executive functions such as decision making and regulating attention–while suppressing activity in other brain regions.
Still, researchers are stumped to explain how these changes in brain patterns work to make hypnotized people feel and see things differently. Recent theories, discussed in the article in Trends by Halligan and Oakley, of University College London, propose that hypnotic suggestions may inhibit or disconnect certain mental processes from the brain’s executive control systems.
Until recently, such hypotheses had remained untested. But in the June 25 issue of Neuron, Yann Cojan of the University of Geneva and colleagues report a direct test.
The researchers put 18 subjects in a brain scanner, instructing them to push a button using one hand or the other. Each trial began with a cue indicating which hand to prepare for movement. After a brief interval, an image of a hand would turn green–signaling to press the button–or red, a command to inhibit any motion. Twelve subjects did half of the trials while hypnotized, with the suggestion that their left hand was “paralyzed,” and the other half in a normal, unhypnotized state. Six subjects did trials without hypnosis under instructions to pretend their left hand was paralyzed.
When volunteers used their right hands, the motor cortex linked up with brain regions that control body movement to carry out the task.
But fMRI scans showed changes in several brain areas when hypnotic paralysis prevented subjects from responding to the “go” signal with their left hands. Under hypnosis, neurons in the brain’s motor cortex fired up as usual to prepare for the task. But when instructed to use the left, or “paralyzed” hand, the motor cortex failed to send signals to motor execution regions. Instead, it directed its signals to another brain region, the precuneus.
The precuneus is a sort of center for self-consciousness. If you’ve ever-pictured yourself falling flat on your face in the middle of an important event, that’s your precuneus working overtime. Its function is to help retrieve memories and images of yourself from the brain’s archives and help to visualize movements.
By rerouting motor signals to the precuneus, hypnosis appeared to decouple the typical relationship between brain areas that generate the signals for hand movement and the areas that carry out such movements. Subjects who were not hypnotized and were asked to fake paralysis showed no such disconnect between these regions.
Because the precuneus is involved in mental imagery and self-awareness, Cojan says, hypnosis appeared to enhance the brain’s self-monitoring processes to allow images generated by suggestion–”your hand is heavy and cannot move”–to guide behavior.
By linking to the precuneus, “the motor cortex is connected to the idea that it cannot move the left hand” Cojan says. “So even if you try to move, it will neglect to send signals to the motor execution areas.”
Because the motor cortex fired up as usual to prepare for the task, the findings suggest that mental images created through hypnotic suggestions work by redirecting normal brain functions rather than actively suppressing them, he adds.
Generating piece of mind
Using insights gleaned from the brain scans of subjects paralyzed under hypnosis, Cojan conducted a follow-up study to see whether something like hypnosis happens in the brains of patients during hysterical paralysis. In such instances, patients become paralyzed even though the condition can’t be traced to any physical or neurological brain damage.
An fMRI study of patients with hysterical hand paralysis did not find the heightened precuneus activity that is seen in hypnosis, Cojan’s group reported in the September NeuroImage.
[ILLUSTRATION OMITTED]
Previously, it had been suggested that hysterical paralysis was “a kind of self-hypnosis,” Cojan says. “Our findings show that’s not the case.”
Halligan points to the recent paralysis studies as examples of how hypnosis can be used to further studies on the nature of hypnosis and to provide insights on a variety of real-life syndromes and disorders.
In 2000, he and Oakley began looking at ways to use hypnosis to simulate psychosomatic conditions, such as hysterical paralysis or hysterical blindness, in the lab. By creating virtual patients through hypnosis, scientists might be able to better understand the basis for such disorders by comparing patients’ brains with hypnotized brains, the researchers reckoned.
Deeley, who treats psychiatric patients at his private practice in London, says using hypnosis also allows him to track brain processes involved in other kinds of disorders that would not ordinarily be possible to study with brain imaging.
In an ongoing series of experiments, he and his colleagues are using hypnosis to study conditions in which patients sense a “lack of control” over their movements or behavior. Such perceptual experiences may be reported by people who experience nonepileptic seizures or who suffer delusions caused by schizophrenia.
By making some targeted suggestions–”Your left hand is now shaking at your side” or “Your right leg is twitching”–the scientists can model a particular symptom in a consistent and controlled way, Deeley says.
“You can’t have somebody having a full-blown seizure within an MRI scanner,” he says. “It’s not safe because they’re moving fast, and you wouldn’t get any useful information. But if you actually restrict an involuntary movement to a particular limb or a hand, it is possible to create a partial model of these involuntary movements.”
Another advantage of hypnosis is that it allows researchers to untangle the many components that make up a complex disorder, such as schizophrenia. In such cases, patients may feel not only that they’re losing control, but also that their actions or behavior are guided by an outside force or agent, such as the CIA.
Scientists then have the problem of sorting out whether a change in brain activity is associated with the physical experience of a movement or whether it is tied to the delusional beliefs behind the movement.
“In such cases, you’ve got two processes going on associated with complex change in brain activity, and you just can’t unpack them in terms of working out what’s associated with what,” Deeley says.
Experimental manipulations using hypnosis could provide a window into a wide range of disorders, he says, and could help explain other types of altered states, such as meditation.
Halligan agrees, noting that hypnosis could be used to simulate various disorders commonly associated with brain injury, such as visual impairment. In a recent study, he used hypnotic suggestions to replicate conditions described by injured soldiers who are still capable of detecting motion in certain visual fields but are unable to make out any distinguishing features of the moving object.
“That’s not to say that the same psychological consequences of pathology seen in patients are somehow replicated in hypnosis,” Halligan says. “But using hypnosis to simulate a specific condition for imaging may tell us which brain systems are involved.” This information may then feed back into the development of new treatments and rehabilitation tools, he says.
Such advancements, however, hinge on learning more about the underlying processes involved in hypnosis itself. Current efforts may help scientists differentiate between the brain structures that play a role in hypnosis and those that are involved in the tasks subjects are asked to perform.
“These are still early days,” Halligan says, noting that it has yet to be seen how well hypnotically simulated disorders will actually match the conditions they’re intended to mimic. Still, he says, hypnosis provides a way to “test and probe.”
Best of all, no pocket watches are involved.
Your brain on hypnosis
Studies show hypnosis reroutes brain signals. Hypnotized people who are told that their left hand is paralyzed show brain patterns (yellow) that differ from those who aren’t hypnotized (red) and from those who aren’t hypnotized but are told to pretend their left hand is paralyzed (green).
[ILLUSTRATION OMITTED]
When told to move their right or “unparalyzed” hand, the motor cortex fired up in all subjects to prepare the hand to move.
When told to move the left hand, the motor cortex again got ready to move in all subjects.
In hypnotized subjects told to move their left, “paralyzed” hand, the motor cortex routed signals to the precuneus, an area involved in mental imagery and memory about oneself. Pretenders (green) did not use the precuneus.
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* Explore the science behind hypnosis at the Hypnosis and Suggestion website: www.hypnosisandsuggestion.org
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Susan Gaidos is a freelance science writer based in Maine.
Well known expert offering free Irritable Bowel Syndrome Advice
| From IN2TOWN LIFESTYLE January 29th 2010 A well known Irritable Bowel Syndrome expert as seen on television is offering people who suffer from Irritable Bowel Syndrome a free one hour consultation over the phone in her effort to make more people aware of what Irritable Bowel Syndrome is and how Irritable Bowel Syndrome therapy can help sufferers. Claire Hegarty who is offering people a free one hour consultation over the phone by phoning 0151 678 3358 or by visitingwww.clairehegarty.co.uk said: “Irritable Bowel Syndrome is not an illness many people know about or even understand and even less people know that Hypnotherapy and complimentary Health can help people who suffer from what is more commonly known as IBS.” Hypnotherapy has become a natural way of dealing with Irritable Bowel Syndrome like acupuncture, which has become very popular for different illnesses and health problems, it was until a few years ago not properly understood how acupuncture can help but now thousands and thousands of people go for acupuncture treatment and this is happening with Hypnotherapy for Irritable Bowel Syndrome . More and more people are now becoming familiar that Hypnotherapy can help with Irritable Bowel Syndrome and this is why more and more doctors and information their patients that they can see a complimentary health expert who can help them with IBS. Hypnotherapy allows a person to tap into a special mental state (the subconscious level of their mind), allowing them to alter the way in which they consciously perceive their health problems, and encourages them to respond to these problems in new ways. How? While they are in this special mental state, the person is given verbal suggestions or provided imagery to assist them in finding relief from their symptoms. The stimulation that the person under hypnosis receives from words and images has a significant impact on the way they function mentally and physically. For instance, imagery used during hypnotherapy for IBS patients would be images that encourage healing. Depending on what the image is, the patient may imagine their intestines expanding and relaxing to let fluids flow through. Hence, this imagery is meant to help the patient with their constipation problem. Why is hypnotherapy an effective IBS treatment? The reason is because hypnosis is a therapy that can help both the body and the mind. Think of hypnosis as a treatment that helps a person put mind over matter. In other words, it’s a way to use the mind to help heal physical ailments. Furthermore, many researchers believe IBS is a primary disorder of the brain/gut axis. The what? The brain/gut axis is the term given to the important relationship between the events that have an affect on the way the central nervous system (brain) functions, and how this resulting function affects the way the intestines function through the intestinal specialized enteric nervous system. Essentially, the mind and body are connected. The state of one’s mind can have positive or negative affects on the way the body functions. For many IBS sufferers, one of the best benefits of hypnotherapy are its ability to reduce the hold stress has on them. Most people with IBS are plagued by negative emotions such as anxiety, tension, and depression, all symptoms of stress that are caused by having to live with an incurable condition. Stress can cause chemical imbalances within the brain that can undermine the immune system and cause an IBS flare up. Hypnosis can decrease the stress one feels about IBS and help a person realize and explore new thoughts and strategies about how to cope with the illness. Hypnotherapy turns the negative to positive.Over the course of 15 years, numerous studies have been conducted on the effects of hypnotherapy on people with IBS. The results have been very successful. In fact, hypnotherapy regularly generates long-term positive results in more than 80% of those who are treated with it. As an additional bonus, hypnotherapy is safe for all ages, and works on 90% of the population. Keep in mind, that like most types of natural remedy for IBS, hypnotherapy usually requires more than one session to be successful and maintain its effectiveness. Free Consultation for Irritable Bowel Syndrome. If you would like a free consultation in IBS then please call 0151 678 3358 or visitwww.clairehegarty.co.uk |






